Intravenous thrombolysis remains a standard treatment for acute ischemic stroke within 4.5 hours after onset. Vascular ...

Atrial fibrillation affects more than 33 million people worldwide and is a leading cause of stroke. 1 Alcohol consumption is ingrained in Western culture, with 57% of American adults drinking ...

Treatment was initiated in 308 participants per group. At week 48, HIV-1 RNA levels of 50 copies per milliliter or higher were found in 5 participants (1.6%) receiving long-acting therapy and in 3 ...

We conducted a phase 2a, multicenter, randomized, double-blind, placebo-controlled, 24-week, parallel-group trial to assess the efficacy and safety of risankizumab, an anti–interleukin-23p19 ...

The authors review the epidemiology, pathophysiology, and treatment of alcohol-associated hepatitis, including the evidence for glucocorticoids and liver transplantation.

The current Phase 2 Trial of Anti α-Synuclein Antibody in Early Parkinson’s Disease (PASADENA) is a three-part, randomized trial assessing the efficacy and safety of low-dose (1500 mg) and high ...

The authors examine the epidemiology, pathogenesis, clinical expression, and differential diagnosis of Behçet’s syndrome, as well as targeted therapeutics.

Adipose tissue glucose transport and GLUT4 levels regulate systemic insulin sensitivity and whole-body energy balance, which have implications for the pathogenesis and treatment of obesity and diab ...

The lifetime risk of cardiovascular disease was 24% (95% confidence interval [CI], 21 to 30) among women and 38% (95% CI, 30 to 45) among men for whom all five risk factors were present. In the ...

Primary central nervous system (CNS) vasculitis, also known as primary angiitis of the CNS, is a rare form of vasculitis that is limited to the brain and spinal cord and causes a variety of ...

A 2017 meta-analysis of 25 studies involving a total of 254,408 patients, including 55,150 with acute kidney injury, 15 showed that the condition was associated with an 86% increase in the risk of ...

Most rotator-cuff tears are degenerative, atraumatic, and more prevalent with age. Nonoperative treatment, including physical therapy, is typically recommended; surgery is considered in some cases.