Scientists at the University of Sydney have uncovered a malfunctioning version of the SOD1 protein that clumps inside brain ...

Groundbreaking research by Sydney University found a new brain protein involved in Parkinson’s disease and a way to modify it ...

Scripts used in The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration. Abstract: Amyotrophic lateral sclerosis can be caused by variants in the ...

Doctors are using a new gene therapy drug from the US, hoping to extend Ms Sabrina's lifespan. Read more at straitstimes.com. Read more at straitstimes.com.

SOD1 G93A is an abbreviation for superoxide dismutase-1 glycine 93 to alanine, which represents the specific mutation type. Hundreds of creative treatments for ALS have been assessed in the SOD1 G93A ...

Hand annotate the region of interest and a sub region of interest containing the neurons (prepare_masks_and_other_processing.ijm) Identify a threshold range to capture SOD1 protein aggregates Create a ...

Tofersen for SOD1 ALS. 2022-09-22. DOI: 10.1056/NEJMdo006683 Save. Permissions ...

Each SOD1 monomer consists of eight anti‐parallel β strands arranged in a β‐barrel structure. Extensive structural and biophysical experiments (Furukawa et al, 2016) have previously established that ...