Scientists at the University of Sydney have uncovered a malfunctioning version of the SOD1 protein that clumps inside brain ...

Groundbreaking research by Sydney University found a new brain protein involved in Parkinson’s disease and a way to modify it ...

Groundbreaking research by the University of Sydney has identified a new brain protein involved in the development of ...

A newly discovered brain protein linked to Parkinson’s offers hope for targeted therapies that could slow or prevent disease ...

Now, scientists at the University of Sydney have made an exciting discovery: they’ve found a new brain protein linked to ...

Dokholyan explained that SOD1 typically exists as a dimer, a protein composed of two identical units. Under certain conditions, SOD1 will change its shape and reassemble itself into a three-unit ...

Using the misfolded SOD1 antibody C4F6, Bosco discovered misfolded SOD1 in four out of nine sporadic ALS cases. The work suggests that at least some ALS cases manifest deformed SOD1, even though the ...

The decision on the SOD1 ALS program does not impact Voyager’s other gene therapy programs; the Company continues to expect IND filings in 2025 from Neurocrine Biosciences for the program in ...

SOD1-ALS is a rare, progressive and fatal neurodegenerative disease that results in the loss of motor neurons in the brain and spinal cord. As ALS progresses, ...

According to a press release from Biogen, Qalsody (tofersen), an antisense oligonucleotide, targets superoxide dismutase (SOD1) mRNA to reduce protein production, became the first News News ...